U.S., Nov. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07230990) titled 'Mechanisms Of Orbitofrontal Stimulation in Depression' on Nov. 06.
Brief Summary: The orbitofrontal cortex (OFC), a region involved in emotional regulation, decision making, and reward processing, is a key area linked to antidepressant response. This study tests whether noninvasive stimulation of the OFC using transcranial magnetic stimulation (TMS) can improve depressive symptoms. TMS uses magnetic fields generated by a coil placed next to the scalp to alter brain activity.
Study Start Date: Jan., 2026
Study Type: INTERVENTIONAL
Condition:
Major Depressive Disorder (MDD)
Intervention:
DEVICE: Sham TMS
The MagVenture MagPro s...