U.S., March 26 -- ClinicalTrials.gov registry received information related to the study (NCT06894004) titled 'Mechanism of Ketogenic Diet-Induced Hypercholesterolemia' on March 10.
Brief Summary: Very-low carbohydrate ketogenic diets can dramatically increase blood cholesterol levels, particularly in normal-weight people, for reasons that are not well understood. This study will enroll normal-weight adults, will identify "responders" who develop high cholesterol on a ketogenic diet, and will measure rates of production and removal of certain types of cholesterol-carrying particles called lipoproteins in responders. The results will clarify the mechanism by which a ketogenic diet can cause high cholesterol in certain susceptible people.
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