Clinical Trial: Longitudinal serum biomarkers at the Onset of Early-Onset Preeclampsia for Predicting Imminent Delivery and maternal-fetal adverse outcomes: A Prospective, Blinded, Multicenter Study (Japan)

Tokyo, Dec. 19 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060106) titled 'Risk Assessment for Predicting Imminent Delivery in Early-Onset Preeclampsia' on Dec. 18.

Study Type: Observational

Primary Sponsor: Institute - The University of Tokyo

Condition: Condition - Preeclampsia Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - While the sFlt-1/PlGF ratio predicts preeclampsia (PE) onset, evidence linking post-onset levels to pregnancy outcomes remains limited. This study aims to evaluate the longitudinal changes in serum biomarkers, particularly sFlt-1 and PlGF, measured at the onset of early-onset PE, and to assess the predictive value f...