U.S., March 22 -- ClinicalTrials.gov registry received information related to the study (NCT06888388) titled 'Long-term Safety of Nipple Sparing Mastectomy in Women with GPV in Breast Cancer' on March 15.
Brief Summary: Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple sparing mastectomy (NSM) is associated with improved psychosocial and sexual well-being and is significantly better for body image and reducing feelings of disfigurement.
Despite this, guideli...