U.S., Jan. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07320716) titled 'Long-Term Immunogenicity of the altSonflex1-2-3 Shigella Vaccine in African Children' on Dec. 22, 2025.
Brief Summary: The current study is a follow-up to 2 previous parent studies, a dose-selection study with 3 different dose-levels of the altSonflex1-2-3 vaccine in a schedule of 3 vaccinations (H06\_01TP study [NCT05073003, 212149]) and a study with an alternate 2 vaccination schedule H06\_02TP study [NCT06663436, 219449]). The current study aims to assess the longevity of the immune response to the selected dose of the altSonflex1-2-3 vaccine 1, 2, and 3 years after the last vaccination in African children. The study involves no n...