U.S., April 5 -- ClinicalTrials.gov registry received information related to the study (NCT06910241) titled 'Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs' on April 02.
Brief Summary: Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for simple laceration repair. Patients who present to the emergency department with a simple laceration will be enrolled in the stu...