U.S., March 11 -- ClinicalTrials.gov registry received information related to the study (NCT06866379) titled 'Involvement of the Septal Nuclei of the Human Brain in Alcohol Use Disorder' on March 04.
Brief Summary: Alcohol activates reward systems located in different areas of the brain i.e. nucleus accumbens, dorsal striatum, extended amygdala and prefrontal cortex. These areas are all part of the reward neurocircuitry which plays an important role in the development of addiction.
A former study, performed on rodents, has shown that a specific area of the forebrain, called the septal nuclei, is associated with the feeling of reward, and hence addiction, when stimulated as well. However whether the septal area is involved in reward and ad...