U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT06799247) titled 'Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis' on Jan. 23.

Brief Summary: The AURORA Study is evaluating the safety, tolerability, and efficacy of an investigational mRNA CAR T-cell therapy known as Descartes-08 in adults with acetylcholine receptor autoantibody -positive generalized myasthenia gravis. Part 1 of the study will last around 6 months. For eligible participants, Part 2 will last around 8 months.

Study Start Date: Feb. 28

Study Type: INTERVENTIONAL

Condition: Myasthaenia Gravis

Intervention: BIOLOGICAL: Decartes-08

Autologous mRNA CAR T-cell the...