U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT06891781) titled 'Investigating Adaptive Deep Brain Stimulation in Parkinson's Disease Management' on March 11.
Brief Summary: The goal of this prospective, multi-center, randomized, double-blind, crossover clinical trial is to evaluate the effectiveness and safety of adaptive DBS (aDBS) and conventional DBS (cDBS) delivered through the AlphaDBS system, in levodopa-responsive Parkinson's disease subjects. Data from previous studies conducted in Europe indicate that the use of the AlphaDBS system is safe and effective in both aDBS and cDBS modes. However, such studies suggest that aDBS may lead to more ON-time without troublesome dyskinesias in some ...