U.S., Dec. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07308808) titled 'Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation' on Oct. 20.
Brief Summary: The goal of this clinical trial is to determine whether Lactobacillus crispatus strains isolated from the lower urinary tracts of adult women can be used as an antibiotic-sparing treatment for urinary symptoms and urinary tract infection (UTI) among adults with neurogenic lower urinary tract dysfunction (NLUTD). The main question[s] it aims to answer are:
1. To identify soluble bactericidal compounds produced by urinary isolates of L. crispatus that kill uropathogenic E. coli (UPEC).
2. To determine if intravesical instillat...