Clinical Trial: Intrathecal Therapy for Adult Tuberculous Meningitis: Impact on Clinical Outcomes

U.S., Feb. 7 -- ClinicalTrials.gov registry received information related to the study (NCT06811792) titled 'Intrathecal Therapy for Adult Tuberculous Meningitis: Impact on Clinical Outcomes' on Jan. 27.

Brief Summary: Tuberculous meningitis (TBM) is the most lethal form of tuberculosis (TB). While anti-TB regimens remain the cornerstone of treatment, spinal injection of dexamethasone is considered a potentially effective adjuvant therapy. However, its impact on mortality and disability remains uncertain. This study analysed all TBM patients admitted to Beijing Chest Hospital affiliated with Capital Medical University from January 1, 2010 to December 31, 2023. Patients were categorised into two groups based on whether they received standard...