Clinical Trial: Intraosseous Vancomycin Into the Medial Malleolus vs Intravenous Administration in Revision Total Knee Arthroplasty

U.S., Dec. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07283068) titled 'Intraosseous Vancomycin Into the Medial Malleolus vs Intravenous Administration in Revision Total Knee Arthroplasty' on Dec. 02.

Brief Summary: Purpose of this study is to compare the efficacy of intravenous and intraosseous antibiotic administration techniques during revision total knee arthroplasty

Study Start Date: Feb. 15, 2026

Study Type: INTERVENTIONAL

Condition: Revision Total Knee Arthroplasty

Intervention: DRUG: Intraosseous Vancomycin

IO vancomycin is administered via an intraosseous cannulation device (Arrow EZ-IO; Teleflex, Morrisville, NC) in the OR after sterile prep of the leg and draping has occurred prior to ...