U.S., July 31 -- ClinicalTrials.gov registry received information related to the study (NCT07093281) titled 'Intranasal LAIV Mucosal Immunity Examination' on July 14.
Brief Summary: The research of the investigators is focused on the understanding how the immune system functions and responds to intranasal vaccines. Intranasal vaccines do not lead to the same changes in the blood that intramuscular vaccines do. Therefore, the investigators want to look at the function of immune (lymphoid) organs that are near the nose. The closest immune organs are the adenoids and tonsils. Mice do not have tonsils allowing for the investigators to answer these questions. Human lymphoid tissue will allow the investigators to better understand the molecular ...