U.S., Dec. 4 -- ClinicalTrials.gov registry received information related to the study (NCT06713174) titled 'Interleukin 8 And10 Levels Changes in Teeth with Necrotic Pulp and Apical Periodontitis' on Nov. 25.
Brief Summary: The goal of this observational study is to evaluate changes in interleukin 8 (IL-8) and interleukin 10 (IL-10) levels in gingival crevicular fluid (GCF) and periapical fluid during root canal treatment in patients with necrotic pulp and apical periodontitis. The main question it aims to answer is:
How do IL-8 and IL-10 levels in GCF and periapical fluid change over the course of treatment?
Participants will:
Provide samples of GCF and periapical fluid at two different time points during their root canal treatment.
U...