U.S., Feb. 15 -- ClinicalTrials.gov registry received information related to the study (NCT06827496) titled 'Initial Oral Antibiotics for Bone and Joint Infections in Children' on Feb. 10.
Brief Summary: Initial oral antibiotic treatment for children and adolescents with uncomplicated bone and joint infections (BJI) has been found non-inferior to initial IV antibiotics in one randomized controlled trial (RCT) (Bybeck Nielsen et al., 2024). The real-world effectiveness of initial oral antibiotics for children and adolescents with BJI is unclear.
This nationwide, prospective, multicenter, real-world cohort study aims to compare the effectiveness and safety of initial oral antibiotic treatment for children and adolescents with uncomplicated ...