U.S., May 24 -- ClinicalTrials.gov registry received information related to the study (NCT06986993) titled 'Impact of Semaglutide on Tobacco Use and Related Health Behaviors' on May 13.
Brief Summary: This pilot randomized trial will assess the impact of 12 weeks of semaglutide administration (vs placebo) on changes in: (i) tobacco use and related factors (nicotine craving, withdrawal, motivation to quit, etc.) and (ii) biological biomarkers of health (e.g., epigenetics, glucose variability via continuous glucose monitoring [CGM], etc.) in adult smokers with obesity (n = 40). We will integrate molecular biology procedures (e.g., epigenetics) to maximize internal validity with real-world smartphone-based ecological momentary assessment (EMA...