U.S., Aug. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07119567) titled 'Impact of Cocaine Use and Withdrawal on Sleep' on July 29.
Brief Summary: This study investigates how cocaine use and withdrawal affect sleep and circadian rhythms in individuals undergoing inpatient detoxification. Using wearable sleep monitors, actigraphy, questionnaires, and hormonal biomarkers, it aims to capture both objective and subjective changes in sleep across three key stages: active use, early withdrawal, and late withdrawal. The study is unique in its ability to explore sleep microstructure, the circadian system's role via melatonin and cortisol measurements, and the dynamic relationship between subjective sleep percept...