U.S., April 26 -- ClinicalTrials.gov registry received information related to the study (NCT06945861) titled 'Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP)' on April 07.
Brief Summary: The general objective of the proposed project is to characterise phenotypically and functionally ADAMTS13-specific memory B lymphocytes and autoreactive T lymphocytes, in particular follicular helper T lymphocytes, in the acute phase of the disease, but also during its progression after treatment. The aim is to highlight their contribution to the initial pathogenic process, their evolution under treatment, and also their involvement in patients who are refractory to immunosuppressive therapies and during relapses. The aim of this project ...