U.S., Feb. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07389525) titled 'Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study' on Jan. 29.
Brief Summary: Immune checkpoint inhibitors (ICIs) (also called "immunotherapy") are an effective family of anti-cancer drugs, but they can cause serious side effects. Some evidence suggests these side effects might happen because ICIs interact with other drugs that you may already be taking, making those drugs work differently, or causing more side effects. The purpose of this study is to see whether ICIs impact how the liver processes other drugs. To do this, participants will be given a probe cocktail of 7 different FDA-approved drugs that are process...