U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07199205) titled 'Hyperuricemia as Early Indication of CKD Progressing in Prediabetic' on Sept. 19.
Brief Summary: Chronic kidney disease (CKD) is a major global health problem, and hyperuricemia has emerged as both a consequence and a potential driver of its progression. Elevated uric acid contributes to renal impairment through oxidative stress, endothelial dysfunction, inflammasome activation, and crystal deposition. Epidemiological studies show that hyperuricemia often precedes CKD and serves as an independent predictor, with prevalence reaching up to 38% among CKD patients.
Prediabetes, another growing health concern, is associated with higher s...