U.S., Feb. 13 -- ClinicalTrials.gov registry received information related to the study (NCT06822374) titled 'Hypertonic Saline in Intracranial Surgery' on Jan. 31.
Brief Summary: This is a prospective, randomized study in patients 8-21 years of age scheduled for an intracranial surgical procedure that requires invasive monitoring of arterial blood pressure. Subjects will be randomized to receive either 0.9% normal saline or buffered 2% hypertonic saline for intraoperative fluid resuscitation.
The primary objective of this study is to compare intraoperative changes in acid-base status and electrolytes based on the type of fluid administered intraoperatively.
The secondary objective is to compare the volume of fluid required for intraopera...