U.S., July 11 -- ClinicalTrials.gov registry received information related to the study (NCT07059546) titled 'Hypersensitivity to Adrenomedullin in Post-Traumatic Headache' on July 01.
Brief Summary: Adrenomedullin is a neuropeptide implicated in the pathogenesis of headache. This study investigates whether adrenomedullin induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
Study Start Date: July 01
Study Type: INTERVENTIONAL
Condition:
Posttraumatic Headache
Intervention:
DRUG: Adrenomedullin
The participants will receive continuous intravenous infusion of 20 mL of 19.9 pmol/kg/min adrenomedullin over 20 minutes.
DRUG: Placebo
The par...