Clinical Trial: HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma

U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT06858735) titled 'HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma' on Feb. 27.

Brief Summary: This study will compare outcomes for M1 iCCA patients treated with and without L-RT by reviewing iCCA patients found to have M1 disease at initial diagnosis at a single institution between 2010 and 2021 who received L-RT.

Study Start Date: Aug. 01, 2025

Study Type: INTERVENTIONAL

Condition: Advanced Intrahepatic Cholangiocarcinoma

Intervention: DRUG: Durvalumab

Given by IV

DRUG: Gemcitabine

Given by IV

DRUG: Cisplatin

Given by IV

Recruitm...