U.S., March 1 -- ClinicalTrials.gov registry received information related to the study (NCT06851754) titled 'Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency' on Feb. 25.

Brief Summary: Background:

Premature ovarian insufficiency (POI) is a condition in which women under the age of 40 years have absent or irregular menstrual cycles. POI can cause infertility, signs of menopause, osteoporosis, and other symptoms. Hormone replacement therapy (HRT) is a treatment that gives women extra hormones, such as estrogen and progesterone. HRT works well in adult women. Researchers want to find the most effective doses and regimens for adolescents.

Objective:

To monitor the effects of HRT on adolescents with POI.

Elig...