U.S., Dec. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07269275) titled 'HLA Eplet Mismatches to Predict Long-term Kidney Transplant Outcomes' on Nov. 25.
Brief Summary: Human leukocyte antigen (HLA) matching evaluates the degree of compatibility between donors and organ transplant recipients and assesses broad antigen differences that may influence immune responses post-transplant. A refined HLA matching method based on examining clusters of amino acids on HLA molecules, named eplets, has been recently developed. This method identifies immunogenic discrepancies that may not be apparent through traditional HLA matching. In recent years, assessment of HLA eplet mismatches has emerged as a promising strateg...