U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07423520) titled 'HemodynamIc eFfects of Lung Collapse and overdIstension During ARDS' on Jan. 07.
Brief Summary: The management ARDS relies on ventilatory strategies aimed at limiting ventilator-induced lung injury (VILI). The setting of PEEP is still subject of debate, as randomized clinical trials comparing standardized higher versus lower PEEP strategies failed to demonstrate a clear survival advantage. Only few studies explored the hemodynamic effects of various PEEP levels depending on lung recruitability. Furthermore, the role of PEEP-mediated lung collapse and overdistention on patients' hemodynamics has yet to be elucidated. In this physiolo...