U.S., April 11 -- ClinicalTrials.gov registry received information related to the study (NCT06922786) titled 'Hemadsorption to Enhance Drug Elimination in Intoxications' on April 02.
Brief Summary: In this trial we assess the effectiveness of applying a hemadsorber (cytosorb(R)) in removing benzodiazepines or tricyclic antidepressants in intoxicated patients admitted to ICU with prolonged impaired consciousness. This is a one arm interventional investigation where a hemadsorption filter is applied in patients fulfilling inclusion criteria 8 hours after admission. Plasma titer of the neurodepressing drug will be collected sequentially both before and after start of hemadsorption to evaluate the speed of drug elimination before and after app...