U.S., Sept. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07172789) titled 'Head dOwn Position Before Endovascular Treatment for Large veSsel Occlusion (HOPES5)' on Sept. 02.
Brief Summary: Recent studies suggest that head-down positioning (HDP) intervention may improve outcomes in ischemic stroke. In the era of reperfusion therapy, a key protective strategy is to administer neuroprotective interventions before recanalization to reduce the loss of the ischemic penumbra, thereby salvaging more penumbral tissue after revascularization and ultimately improving clinical outcomes. Based on this concept, and considering the neuroprotective effects of HDP, the investigators hypothesize that HDP intervention prior...