U.S., Jan. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07313020) titled 'Handheld MPI Imaging to Track Stem Cells in Osteoarthritis' on Dec. 17, 2025.
Brief Summary: This clinical trial aims to evaluate the use of a handheld Magnetic Particle Imaging (MPI) device for real-time, non-invasive monitoring of human umbilical cord-derived mesenchymal stromal cells (UC-MSCs) in patients with knee osteoarthritis (OA). The primary objective is to visualize and quantify the distribution, retention, and survival of SPIO (superparamagnetic iron oxide)-labeled MSCs within the joint space following intra-articular injection. By correlating MPI signal dynamics with established clinical outcomes (e.g., WOMAC, VAS scores)...