U.S., April 9 -- ClinicalTrials.gov registry received information related to the study (NCT06916390) titled 'GUselkumAb inteRvention and DIet evaluAtioN for Pouchitis' on March 21.
Brief Summary: Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) is considered the procedure of choice in patients with ulcerative colitis (UC) refractory to medical therapy or with neoplasia. The most common complication after IPAA is the development of pouchitis. Pouchitis is clinically characterized by variable symptoms including increased stool frequency, altered consistency, bloody stools, abdominal cramping, urgency, and incontinence. Symptomatic pouchitis longer than four weeks is considered chronic pouchitis.
The conventional tr...