U.S., April 2 -- ClinicalTrials.gov registry received information related to the study (NCT06905340) titled 'Guiding Opioid Administration by Nociception Level Index (NOL) in Patients with Regional Anesthesia' on March 25.

Brief Summary: General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception. An alternative approach to the intraoperative administration of high potency opioids to achieve antinociception during surgery is combining general anesthesia with regional anesthesia. Modern general anesthesia aims to avoid an overdose of opioid analgesics and reduce side-effects of opioid administration. Quality and safety of general anesthesia are of major clinical i...