U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT06985407) titled 'Grape Extract and Exercise Effects on Blood Pressure' on May 06.
Brief Summary: Exercise and grape extract intake (i.e., polyphenol-rich product) can independently improve blood pressure and endothelial function in prehypertensive individuals. Nevertheless, their combined effects remain unexplored. Furthermore, since the biological pathways targeted by both interventions are similar, they could overlap and be amplified by one another, promoting additive or synergistic effects. Animal model studies have reported that a grape seed extract intake prevents exercise-induced oxidative stress, which could improve vascular dysfunction. Furth...