U.S., Sept. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07193134) titled 'GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment' on Sept. 16.
Brief Summary: This study is being done to find out if a new type of skin graft, called GMEB-SASS, is safe and effective for helping wounds heal in people with RDEB (Recessive Dystrophic Epidermolysis Bullosa).
The GMEB-SASS graft contains two types of living skin cells: keratinocytes and fibroblasts. It is made in a laboratory using a small sample of the patient's own skin.
To help the patient's skin cells produce a missing protein called type VII collagen, scientists grow the patient's cells in the lab and use a virus-like tool (called a retroviral vect...