U.S., Sept. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07154719) titled 'GLP-1R Actions on Muscle and the Skeleton' on Aug. 22.
Brief Summary: The GRAMS study objectives are to assess the musculoskeletal changes that occur after weight loss using GLP-1 based therapy. A lifestyle intervention with diet and exercise is included to assess any mitigating effects are provided, versus a control group with regular exercise and diet.
Study Start Date: Sept. 01
Study Type: INTERVENTIONAL
Condition:
Musculoskeletal Abnormalities
Obesity
Sarcopenic Obesity
Osteoporosis
Drug Effect
Intervention:
DRUG: Tirzepatide
GLP-1 based treatment for obesity
BEHAVIORAL: Lifestyle toolkit
2 ABBOTT protein shakes daily a...