U.S., Nov. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07251725) titled 'GEN-FPF: Genetic Exploration of Familial Pulmonary Fibrosis' on Sept. 25.
Brief Summary: Pulmonary fibrosis (PF) is a progressive lung disease marked by tissue scarring and impaired breathing. Familial pulmonary fibrosis (FPF) makes up 10-20% of PF cases and shares features with idiopathic PF (IPF), but the genetic causes of FPF are not fully understood.
This study focuses on uncovering the genetic basis of FPF by analyzing families with multiple affected members. It targets genes involved in fibrogenesis and surfactant disorders, as familial cases often appear earlier and progress more rapidly than sporadic ones.
Understanding FP...