U.S., Jan. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07337993) titled 'Fungal Empyema Thoracis' on Jan. 03.
Brief Summary: Background:
Fungal empyema thoracis is a rare but life-threatening pleural infection caused by fungal organisms such as Aspergillus and Candida species. It typically occurs in immunocompromised or debilitated patients and carries a high mortality rate. Conventional management involves systemic antifungal therapy and surgical decortication; however, many patients are unfit for surgery due to poor clinical status or multiple comorbidities. The use of local intrapleural antifungal therapy remains poorly studied.
Objective:
This study aims to evaluate the efficacy and safety of pleu...