U.S., June 25 -- ClinicalTrials.gov registry received information related to the study (NCT07033364) titled 'Functional Liver After SBRT' on June 13.
Brief Summary: In this study, we aim to determine the dose-effect relationship between radiation dose and liver function by performing a hepatobiliary scintigraphy (HEBIS) before and after stereotactic body radiotherapy (SBRT) for patients with liver metastases. HEBIS is a nuclear imaging technique to quantitatively assess liver function. It better predicts the risk of postsurgical liver failure compared to volumetry alone. To prevent liver failure after SBRT, current clinical dose constraints require that >= 700 ml of normal liver should receive less than 15 Gy in 3 fractions. The exact loca...