U.S., June 4 -- ClinicalTrials.gov registry received information related to the study (NCT07001891) titled 'Functional Connectivity of the Interoceptive Network in RLS' on May 13.
Brief Summary: Restless Legs Syndrome (RLS) is a sensorimotor disorder primarily characterized by an irresistible urge to move the legs while at rest. A key hypothesis suggests that RLS symptoms are linked to abnormal brain function in processing internally generated stimuli, particularly interoception. This distorted perception of the internal bodily state leads to maladaptive behaviors, which may manifest across a wide range of medical and psychiatric disorders. Here, the investigators hypothesize that dysfunction in the insular cortex (IC) may result in a fail...