Clinical Trial: Fiber-Enriched Enteral Nutrition and Opioid-Induced Constipation in the ICU

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07201428) titled 'Fiber-Enriched Enteral Nutrition and Opioid-Induced Constipation in the ICU' on Sept. 23.

Brief Summary: Opioid use for sedation and analgesia is widespread among mechanically ventilated ICU patients, often leading to gastrointestinal dysfunction and opioid-induced constipation (OIC). While enteral nutrition (EN) is routinely used in critical care, the role of fiber-enriched EN formulas in preventing OIC remains unclear. This prospective quasi-randomized study aims to evaluate whether fiber-containing EN products reduce the incidence and severity of OIC compared to fiber-free formulations in intubated ICU patients. The findings may c...