U.S., Jan. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07331441) titled 'External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery' on Dec. 28, 2025.
Brief Summary: Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor functional recovery. Current analgesic techniques such as neuraxial block have safety concerns (e.g., hypotension, neurological injury), while transversus abdominis plane (TAP) block is ineffective for blocking the lateral cutaneous branches of intercostal nerves in the ...