Clinical Trial: Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite with the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAP

U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT06881732) titled 'Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite with the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAP' on Feb. 27.

Brief Summary: The goal of this clinical trial is to learn if the genetically-modified malaria parasite NF54/iGP3 will safely infect humans with malaria. The investigators will also determine how the parasite grows in humans, and the effect of anti-malarial drugs.

Researchers will use a controlled human malaria infection (CHMI) model to infect participants with malaria to observe the development of the disease, collect malaria-infected blood, and then treat the participants ...