U.S., Sept. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07171619) titled 'Evaluate the Effects of Famotidine or Rabeprazole on the PK of Nirogacestat' on Aug. 07.

Brief Summary: This study will evaluate the effects of the H2 blocker famotidine or the PPI rabeprazole on the PK of nirogacestat in healthy male participants

Study Start Date: Sept. 09

Study Type: INTERVENTIONAL

Condition: Healthy

Intervention: DRUG: Nirogacestat

oral dose of 150 mg nirogacestat

DRUG: Nirogacestat and Famotidine

oral dose of 150 mg nirogacestat & oral dose of 40 mg famotidine

DRUG: Nirogacestat and Rabeprazole

oral dose of 150 mg nirogacestat and oral dose of 20 mg rabeprazole

Recruitment Status: RECRUITING

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