Clinical Trial: Evaluate the Effect of Tirazamine on Primary Liver Cancer.

U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT06848556) titled 'Evaluate the Effect of Tirazamine on Primary Liver Cancer.' on Feb. 19.

Brief Summary: This Phase I/II trial aims to evaluate the pharmacokinetics, efficacy, and safety of tirapazamine administered via hepatic artery injection followed by TACE in patients with intermediate-stage HCC. The trial will compare the outcomes of TATE with standard TACE.

Study Start Date: May 14, 2021

Study Type: INTERVENTIONAL

Condition: Hepato Cellular Carcinoma (HCC)

Intervention: DRUG: tirapazamine

Intra-arterial injection into the tumor feeding artery

PROCEDURE: Transarterial Embolization

Lipiodol and Gelfoam used to embolize tumor vessels and...