U.S., July 12 -- ClinicalTrials.gov registry received information related to the study (NCT07059988) titled 'Endogenous Energy Production in Critically Ill Patients' on June 23.
Brief Summary: The aim of this study is to investigate when critically ill patients transition from a non-suppressible catabolism to a normal response to feeding.
Endogenous production of glucose, fat and protein will be studied on a minimum of two occasions in mechanically ventilated ICU patients, in a fasted state and during parenteral nutrition. Substrate kinetics are estimated by a tracer dilution method using infusions of isotopically labeled glucose, glycerol and phenylalanine. Blood sampling for metabolomics analysis will be performed to elucidate potential...