U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07130253) titled 'Efficacy of Vonoprazan-based Rescue Therapy for H. Pylori Eradication' on Aug. 12.
Brief Summary: 1. This study aims to compare the efficacy of empirical vonoprazan-based therapy versus susceptibility-guided vonoprazan-based therapy for third-line eradication of H. pylori.
2. We also plan to explore the impact of eradication therapy on gut microbiota, fecal antibiotic resistance, and metabolic parameters before and after treatment.
Study Start Date: Aug. 18
Study Type: INTERVENTIONAL
Condition:
HELICOBACTER PYLORI INFECTIONS
Intervention:
DRUG: Vonoprazan based ET
Empirical therapy Based on drug history: Levofloxacin sequent...