U.S., Jan. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07319208) titled 'Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients.' on Dec. 01, 2025.

Brief Summary: The purpose of this study is to demonstrate the efficacy of early continuous intravenous infusion of hypertonic saline solution (HSS) to improve survival and independence in daily life activities (at 6 months) of patients with traumatic brain injury at high risk of intracranial hypertension.

Study Start Date: Jan. 01

Study Type: INTERVENTIONAL

Condition: TBI Traumatic Brain Injury

Intervention: DRUG: Hypertonic saline solution

Continuous infusion of HSS (NaCl 20%) for 48 hours (can be prolonge...