U.S., Aug. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07099157) titled 'Efficacy and Safety of Brivudine in the Treatment of Herpes Zoster' on July 18.
Brief Summary: This multicenter RCT aims to compare the efficacy and safety of Brivudine versus Famciclovir in treating acute herpes zoster. Primary objective: Evaluate pain reduction via Numeric Pain Rating Scale (NPRS) at Day 30. Secondary objectives: Compare NPRS at Day 3/Day 7/Day 14/Day 90, time to lesion resolution, Postherpetic Neuralgia (PHN) incidence, and safety.
Study Start Date: Sept. 01
Study Type: INTERVENTIONAL
Condition:
Herpes Zoster
Intervention:
DRUG: Brivudine
brivudine 125 mg per dose, once daily, 7 days
DRUG: Famciclovir
ora...