U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07377097) titled 'Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects' on Dec. 11, 2025.

Brief Summary: The aim of this prospective interventional study is to investigate the metabolic effects of consuming artificial and natural sweeteners in persons with prediabetes. Prediabetes is a condition characterized by blood sugar levels that are elevated above normal but not yet meeting the criteria for type 2 diabetes. This condition markedly increases the risk of progressing to type 2 diabetes, which in turn can lead to complications including cardiovascular diseases.

Artificial sweeteners such as saccharin and sucr...