U.S., July 16 -- ClinicalTrials.gov registry received information related to the study (NCT07065942) titled 'Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated Patients' on July 04.
Brief Summary: Constipation is the most common gastrointestinal manifestation in diabetic patients. Emerging evidence suggests that gut microbiota dysbiosis may contribute to the pathogenesis of diabetes, highlighting the need to investigate its role in diabetic constipation, though current research remains limited.
Current management of diabetic constipation primarily relies on bulk-forming and osmotic laxatives. Additionally, microbiome-modulating agents (e.g., probiotics, prebiotics, and synbiotics) may serve as adjunctive therapi...