U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT06906224) titled 'Effects of Buspirone Combined with Clozapine' on March 19.
Brief Summary: This study aimed to evaluate the enhancing effects of different doses of buspirone on psychiatric symptoms and cognitive function in patients with schizophrenia. The investigators adopted a prospective, randomised, double-blind, placebo-controlled study design and included 46 patients with schizophrenia being treated at the Fourth People's Hospital of Wuhu. The patients were randomly divided into three groups: the control group, the low-dose group and the high-dose group. The control group received clozapine monotherapy, while the experimental groups received ...